442 次機械超負荷下調(diào)核糖體蛋白通過信號促進軟骨細胞衰老和骨關(guān)節(jié)炎進展 2024-10-10
RPL35 downregulated by mechanical overloading promotes chondrocyte senescence and osteoarthritis development via Hedgehog-Gli1 signalingKeywords: Chondrocyte; Hedgehog pathway; Ost
464 次軟骨細胞生化介質(zhì)與機械應力影響原發(fā)性膝骨關(guān)節(jié)炎差異反應 2024-10-10
The interplay between biochemical mediators and mechanotransduction in chondrocytes: Unravelling the differential responses in primary knee osteoarthritisKeywords: Biochemical medi
389 次利用染色質(zhì)免疫共沉淀測序技術(shù)ChIP-seq等揭示頭頸鱗癌免疫逃逸機制 2024-10-9
免疫逃逸是癌癥進展的關(guān)鍵里程碑,是腫瘤免疫治療的理論基礎(chǔ)。頭頸部鱗狀細胞癌((head and neck squamous cell carcinoma, HNSCC))是全球最常見的惡性腫瘤之一,傳統(tǒng)治療選擇包括手術(shù)切除、放
640 次PI3KCIIα自噬防小鼠低剪切應力引起的內(nèi)皮功能障礙與動脈粥樣硬化 2024-9-10
PI3KCIIα-Dependent Autophagy Program Protect From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in MiceKeywords: atherosclerosis; autophagy; end